Ultra-rapid Electrophilic Cysteine Arylation
Bradley M. Lipka, Daniel S. Honeycutt, Gregory M. Bassett, Taylor N. Kowal, Max Adamczyk, Zachary C. Cartnick, Vincent M. Betti, Jacob M. Goldberg, and Fang Wang
J. Am. Chem. Soc. 145,听23427鈥23432 (2023) DOI:
Mobile zinc as a modulator of sensory perception
Jacob M. Goldberg and听Stephen J. Lippard
FEBS Lett. 597, 151鈥165 (2023) DOI:
Rapid Electrophilic Cysteine Arylation with Pyridinium Salts
Bradley M. Lipka, Vincent M. Betti, Daniel S. Honeycutt, Daniel L. Zelmanovich, Max Adamczyk, Ruojun Wu, Harrison S. Blume, Caitlin A. Mendina, Jacob M. Goldberg, and Fang Wang
Bioconjugate Chem. 33, 2189鈥2196 (2022) DOI:
Cross-伪/尾 polymorphism of PSM伪3 fibrils
Olivia M. Cracchiolo, Dean N. Edun, Vincent M. Betti, Jacob M. Goldberg, and Arnaldo L. Serrano
Proc. Natl. Acad. Sci. U. S. A. 119, e2114923119 (2022) DOI:
Mechanisms Underlying Long-Term Synaptic Zinc Plasticity at Mouse Dorsal Cochlear Nucleus Glutamatergic Synapses
Nathan W. Vogler, Vincent M. Betti, Jacob M. Goldberg and Thanos Tzounopoulos
J. Neurosci. 40, 4981-4996 (2020) DOI:
Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in 尾鈥怌ells
Miseon Lee, Basudeb Maji, Debasish Manna, Sevim Kahraman, Ruth M. Elgamal, Jonnell Small, Praveen Kokkonda, Amedeo Vetere, Jacob M. Goldberg, Stephen J. Lippard, Rohit N. Kulkarni, Bridget K. Wagner, and Amit Choudhary
J. Am. Chem. Soc. 142, 6477鈭6482 (2020) DOI:
Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn2+听allows tracking of lysosomal Zn2+听辫辞辞濒蝉听
Yu Han, Jacob M. Goldberg, Stephen J. Lippard, and Amy E. Palmer
Sci. Rep.听8, 15034 (2018)听DOI:
New Tools Uncover New Functions for Mobile Zinc in the Brain
Jacob M. Goldberg and听Stephen J. Lippard
Biochemistry听57, 3991鈥3992 (2018)听DOI:
Photoactivatable Sensors for Detecting Mobile Zinc
Jacob M. Goldberg, Fang Wang, Chanan D. Sessler, Nathan W. Vogler, Daniel Y. Zhang, William H. Loucks, Thanos Tzounopoulos, and Stephen J. Lippard
J. Am. Chem. Soc.听140, 2020鈥2023听(2018)听DOI:
鈥
CF2H, a Hydrogen Bond Donor
Chanan D. Sessler, Martin Rahm, Sabine Becker, Jacob M. Goldberg, Fang Wang, and Stephen J. Lippard
J. Am. Chem. Soc.听139,听9325鈥9332 (2017)听DOI:
鈥听
Challenges and Opportunities in Brain Bioinorganic Chemistry
Jacob M. Goldberg and Stephen J. Lippard
Acc. Chem. Res.听50, 577鈥579 (2017)听DOI:
Metalloneurochemistry and the Pierian Spring: 鈥楽hallow Draughts Intoxicate the Brain鈥
Jacob M. Goldberg, Andrei Loas, and Stephen J. Lippard
Isr. J. Chem.听56,听791鈥802 (2016)听DOI:
AMPA Receptor Inhibition by Synaptically Released Zinc
Bopanna I. Kalappa, Charles T. Anderson, Jacob M. Goldberg, Stephen J. Lippard, and Thanos Tzounopoulos
Proc. Natl. Acad. Sci. U. S. A.听112, 15749鈥15754 (2015)听DOI:
On the use of thioamides as fluorescence quenching probes for tracking protein folding and stability
E. James Petersson, Jacob M. Goldberg, and Rebecca F. Wissner
Phys. Chem. Chem. Phys.听16, 6827-6837 (2014)听DOI:
鈥
Thioamide-Based Fluorescent Protease Sensors
Jacob M. Goldberg, Xing Chen, Nataline Meinhardt, Doron C. Greenbaum, and E. James Petersson
J. Am. Chem. Soc.听136, 2086鈥2093 (2014)听DOI:
Efficient Synthesis and In Vivo Incorporation of Acridon-2-ylalanine, a Fluorescent Amino Acid for Lifetime and F枚rster Resonance Energy Transfer/Luminescence Resonance Energy Transfer Studies
Lee C. Speight, Anand K. Muthusamy, Jacob M. Goldberg, John B. Warner, Rebecca F. Wissner, Taylor S. Willi, Bradley F. Woodman, Ryan A. Mehl, and E. James Petersson
J. Am. Chem. Soc.听135, 18806-18814 (2013)听DOI:
Thioamide Quenching of Fluorescent Probes through Photoinduced Electron Transfer: Mechanistic Studies and Applications
Jacob M. Goldberg, Solongo Batjargal, Benson S. Chen, and E. James Petersson
J. Am. Chem. Soc.听135, 18651-18658 (2013)听DOI:
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
Glen Liszczak, Jacob M. Goldberg, H氓vard Foyn, E. James Petersson, Thomas Arnesen, and Ronen Marmorstein
Nat. Struct. Mol. Biol.听20, 1098-1105 (2013)听DOI:
Native Chemical Ligation of Thioamide-Containing Peptides: Development and Application to the Synthesis of Labeled 伪-Synuclein for Misfolding Studies
Solongo Batjargal, Yanxin J. Wang, Jacob M. Goldberg, Rebecca F. Wissner, and E. James Petersson
J. Am. Chem. Soc.听134, 9172-9182 (2012)听DOI:
Minimalist Probes for Studying Protein Dynamics: Thioamide Quenching of Selectively Excitable Fluorescent Amino Acids
Jacob M. Goldberg, Lee C. Speight, Mark W. Fegley, and E. James Petersson
J. Am. Chem. Soc.听134, 6088-6091 (2012)听DOI:听
Thioamide Quenching of Intrinsic Protein Fluorescence
Jacob M. Goldberg, Rebecca F. Wissner, Alyssa M. Klein, and E. James Petersson
Chem. Commun.听48,听1550-1552 (2012)听DOI:
Thioamides as Fluorescence Quenching Probes: Minimalist Chromophores to Monitor Protein Dynamics
Jacob M. Goldberg, Solongo Batjargal, and E. James Petersson
J. Am. Chem. Soc.听132, 14718-14720 (2010)听DOI: